Duloxetine appears to be less cardiotoxic and is licensed in the US and EU for alleiating DPN. 度洛西汀似乎心脏毒性较小,已在美国和欧洲获得使用许可用于治疗DPN。
The team then conducted mouse studies on the new drug and showed that WBZ_4 maintained the anticancer activity of imatinib but is less cardiotoxic. 研究小组随后进行的小鼠研究新的药物,并表明wbz_4保持着抗癌活性的伊马替尼,但较少的心脏。
Mismatches between myocardial fatty acid uptake and utilization lead to the accumulation of cardiotoxic lipid species,and cause lipotoxic cardiomyopathy. 心肌游离脂肪酸的摄入和利用的失协调导致心肌中脂质积聚并进而引起脂毒性心肌病。
It's venom possess neurotoxic, cardiotoxic and hemotoxic properties.The clinical features of cobra bite are various, depend on the species and the ratio of the venous component. 眼镜蛇蛇毒同时具有神经性毒性、心脏毒性及溶血的特性,其临床变化为多变性的,依各地的蛇种及蛇毒成分比例的不同而有所不同。
At present,lipotoxic cardiomyopathy has been found in numerous transgenic mouse models,and proves that the accumulation of cardiotoxic lipid species is associated with lipotoxic cardiomyopathy. 目前,脂毒性心肌病已在大量的转基因小鼠模型中发现,证明了有心脏毒性的脂质积聚与脂毒性心肌病是相关联的。
"These results are proocatie and suggest that exposure to trauma and prolonged stress not only may increase the risk for serious mental health problems but are also cardiotoxic," they conclude. 他们总结到:“这些结果很令人兴奋,表明了创伤暴露和长期的应激不止能增加严重精神疾病的发病风险,还能具有心脏毒性。”