Objective: Pharmacokinetics of FPA PVP coprecipitate was studied in order to provide reference for clinical use. 目的:通过对诺氟沙星-聚维酮(FPA-PVP)共沉淀物在人体内药物动力学考察,为临床用药提供理论参考。
Conclusion: To make coprecipitate with PVP as warrier is one of the ways in order to enhance bioavailability of the difficult soluble drugs. 26%25。结论:将难溶性药物制成以亲水性高分子材料为载体的共沉淀物,对于提高难溶性药物的生物利用度是有效的方法之一。