In this review,the choice of excipients, such as disintegrant, adhesive are summarized in formula design of dispersible tablet. 综述了分散片处方设计中崩解剂、粘合剂等辅料的考虑和选用。
The granulation solvent mixed with the model drug and water soluble materals, a binder, and a disintegrant, to form a wet mass. 造粒时乃使用水混合，模式药物和水溶性高分子材料，黏合剂，及崩散剂，形成湿团。
METHODS Ls-HPC was used as the disintegrant to prepare the tablets in 2 ways: endo and exo,and we investigated the stability of heat,moist and light. 方法选用低取代羟丙基纤维素等为崩解剂,采用崩解剂内加和外加相结合的方法制成分散片,并对其热、湿、光等稳定性进行考察,以总黄酮进行质量控制。
RESULTSThe amount of disintegrant s, the coating weight and the concentration of the pore former had significa nt e ffects on the lag ... 崩解剂的用量、包衣液中致孔剂的用量及包衣膜的厚度为影响药物体外释放的主要因素,可以根据需要调节药物的释放时滞。
In vitro release of enteric capsules of Poecilobdella manillensis Lesson extract using sodium carboxy-methyl starch as disintegrant was investigated. 测定了以羧甲淀粉钠为崩解剂的菲牛蛭提取物肠溶胶囊的体外释放。
The curing agent of TMCH is nontoxic,and it's disintegrant has low odor.It had passed the cognizance of FDA,and it can fill the request of edible industry. TMCH硫化剂无毒,其分解物气味淡,已通过美国FDA认证,符合食品行业要求。
