In high enough therapeutic doses, Phenobarbital induces anesthesia. 足够的治疗剂量可诱发麻醉。
Phenobarbital (PB) and dexamethasone (DEX) are P450 inducers while troleandomycin (TAO) can inhibit P4503A activity. 苯巴比妥(phenobarbital，PB)是P4502B、P4502C和3A的强诱导剂； 而地塞米松(dexamethasone，DEX)和三乙酰竹桃霉素(troleandomycin，TAO)则分别是P4503A的强诱导剂和抑制剂。
Long-acting barbiturates (e.g., barbital and phenobarbital) are used to treat epilepsy.Intermediate ones (e.g. 长效巴比妥酸盐（如巴比妥和苯巴比妥）被用来治疗癫痫；
Phenobarbital is a respiratory depressant.The degree of respiratory depression is dependent upon the dose. 苯巴比妥为呼吸抑制剂，呼吸抑制程度取决于剂量。
Midazolam, a sedative in the benzodiazepine group, and phenobarbital would help suppress Jeanna's brain activity. 镇静剂米诺达（midazolam，属于苯二氮平家族）与苯巴比妥（phenobarbital）则有助于抑制金娜脑子的活动。
Phenobarbital may also inhibit calcium channels, resulting in a decrease in excitatory transmitter release. 苯巴比妥还对钙通道起抑制作用，减少兴奋性递质的释放。
