In losartan treatment group,spirolactone treatment group and combination treatment group,compared with control group,ventricular weight(VW)/body weight(BW) ratio was significantly decreased (P 氯沙坦钾组、螺内酯组及联合用药组全心重量(VW)、体重(BW)均较安慰剂组降低(P<0.;05);联合用药组VW/BW较氯沙坦钾组、螺内酯组降低更明显(P<0